Trends in prescribing montelukast in patients with asthma in real-life: Results from the Turkish adult asthma registry.

Montelukast, a leukotriene receptor antagonist (LTRA) approved for the treatment of asthma and allergic rhinitis, is widely used, though real-world data on its application in asthma management remain limited. This registry-based study evaluated the use of montelukast in adult asthma patients, examining demographic and disease characteristics, asthma control status, asthma phenotypes, presence of atopy, and treatment regimens. Among 2053 patients analyzed, 61.

Factors influencing the prescription of add-on long-acting muscarinic antagonists in real-world asthma management: Insights from a national registry.

Current guidelines recommend adding long-acting muscarinic antagonists (LAMAs) in patients with uncontrolled asthma, despite the use of moderate to high doses of inhaled steroid-long-acting beta agonists (ICS/LABA). This study aims to analyze the factors related to the prescription of add-on LAMA in clinical practice for asthma patients, shedding light on physicians' preferences. This study included adult asthma patients on add-on LAMA and ICS/LABA monitored for at least one year in a national registry comprising 2053 asthmatics.

Analysis of peripheral lymphocyte subsets and T-cell exhaustion in SARS-CoV-2 Infection.

Introduction: : Immune responses against Coronavirus (SARS-CoV-2) may be highly complex. It has been suggested that T-cell fatigue develops due to continuous stimulation of T-cells by SARS-CoV-2 in Coronavirus disease-2019 (COVID-19). It was aimed to assess peripheral lymphocyte subsets and T-cell exhaustion in various clinical courses of the disease in patients diagnosed with COVID-19.

EU27 regional trade networks for medical products in fight against Covid-19 pandemic: Quantifying vulnerability and self sufficiency in critical inputs.

The Covid-19 pandemic spread fast due to a lack of vaccines and a severe shortage of medical products to treat and combat the disease. Many studies have focused on the characteristics of extant global supply chains and trade networks that are determined by globalization drives for production to low-cost countries and the technological complexity of products with many components distributed globally. This, along with the lockdown of many sectors and national policies that divert exports for domestic use, are reasons for lack of access, especially, in Western countries to these products.

Exploration on terrorism, ecological footprint and environmental sustainability in countries with the most terrorism antecedent: Accessing evidence from panel fourier analysis.

Amidst increased concerns for global security and ecological balance, the intricate interconnectedness between terrorism and environmental sustainability has attracted significant attention in the existing literature. To this end, the present study explores the interaction among environmental degradation, terrorism, and foreign direct investments in 17 countries with the most terrorism antecedents over the 2002-2018 period through the Panel Fourier cointegration test and the Panel Fourier Toda-Yamamoto causality test. The present study also leverages recent and robust panel analysis for evidence-based results and inferences for policy formulation.