Torsade de pointes: a severe and unknown adverse effect in indoramin self-poisoning.

We report the two first cases of torsade de pointes associated with QT interval prolongation following a large ingestion of indoramin.

Physical activity and sedentary lifestyle in children as time-limited functions: usefulness of the principal component analysis method.

This study was designed to examine the hourly variation in and the interplay between physical activity and sedentary behavior (SB) in order to highlight key time periods for physical activity interventions for children. Data for physical activity and SB obtained with ActiGraph in 56 boys and 47 girls aged from 8 to 11 years. These data were divided into sixty minute-time samples for moderate-to-vigorous physical activity (MVPA) and SB, and analyzed using a principal component analysis (PCA) and correlation statistics.

Methodological approach for the evaluation of the performances of medical intensive care units.

Purpose: The purpose of the study was to present a methodological approach enabling the comparison of clinical and economic performances of intensive care units and a graphical visualization based on these 2 dimensions.

Patients And Methods: A retrospective analysis of a database of 666 patients admitted in intensive care units over a period of 2 consecutive months.

Results: Calculation of clinical performance is based on the difference between the mortality observed and forecast from the Simplified Acute Physiology Score version 2.

Can dynamic indicators help the prediction of fluid responsiveness in spontaneously breathing critically ill patients?

Objective: To investigate whether the respiratory changes in arterial pulse (DeltaPP) and in systolic pressure (DeltaSP) could predict fluid responsiveness in spontaneously breathing (SB) patients. Because changes in intrathoracic pressure during spontaneous breathing (SB) might be insufficient to modify loading conditions of the ventricles, performances of indicators were also assessed during a forced respiratory maneuver.

Design: Prospective interventional study.

Multiple-drug-resistant bacteria in patients with severe acute exacerbation of chronic obstructive pulmonary disease: Prevalence, risk factors, and outcome.

Objective: To determine prevalence, risk factors, and effect on outcome of multiple-drug-resistant (MDR) bacteria in patients with severe acute exacerbation of chronic obstructive pulmonary disease.

Design: Prospective, observational, cohort study.

Setting: Thirty-bed medical intensive care unit (ICU) in a university hospital.