Publications by authors named "S Sonomtseren"

Mongolian people possess a unique dietary habit characterized by high consumption of meat and dairy products and fewer vegetables, resulting in the highest obesity rate in East Asia. Although obesity is a known cause of type 2 diabetes (T2D), the T2D rate is moderate in this population; this is known as the "Mongolian paradox." Since the gut microbiota plays a key role in energy and metabolic homeostasis as an interface between food and body, we investigated gut microbial factors involved in the prevention of the co-occurrence of T2D with obesity in Mongolians.

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Objective: To evaluate the effectiveness of a weight loss intervention in Mongolian adults with newly diagnosed type 2 diabetes mellitus and with BMIs ≥ 25.0 kg/m.

Methods: Eighty participants (33 men/47 women) aged 32-56 years old received education sessions to improve nutritional habits and increase physical activity.

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Article Synopsis
  • Recent genome-wide association studies have found over 40 genetic variants linked to type 2 diabetes, but results vary across different populations.
  • A study investigated the genetic risks of type 2 diabetes in a North Asian population of Mongolians, using genetic samples from 393 individuals.
  • The strongest associations were found in potassium channel genes KCNQ1 and ABCC8, suggesting their role in diabetes risk may be influenced by the region's harsh environment.
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