Arbeitsbedingte Synkanzerogenese an der Haut - Zur kombinatorischen Einwirkung zweier Karzinogene der Berufskrankheiten-Liste.

Hintergrund: Die Synkanzerogenese am Hautorgan, wissenschaftlich unstrittig, spiegelt sich im monokausal geleiteten Berufskrankheiten (BK)-Recht nicht wider. Nichtmelanozytäre Hauttumoren und deren Vorläuferläsionen können nur nach Einzelprüfung der BK-Nrn. 5103 und 5102 anerkannt werden.

Occupational syncarcinogenesis in the skin - combined effects of two carcinogens from the German occupational disease list.

Background: Though scientifically undisputed, cutaneous syncarcinogenesis is not reflected in German occupational disease (OD) regulations, which tend to be guided by the tenet of monocausality. Recognition of nonmelanoma skin cancer (NMSC) and its precursor lesions as OD requires individual assessment as to whether the requirements pursuant to either OD 5103 (occupational exposure to natural UV radiation) or OD 5102 (occupational exposure to polycyclic aromatic hydrocarbons) are fulfilled.

Methods: Retrospective analysis of 28 patients (median age 72.

[Delayed anaphylaxis after ingestion of meat. Carbohydrate epitope galactose-α-1,3-galactose as cause of severe anaphylactic reactions].

The correlation between anaphylaxis after consumption of meat and the carbohydrate epitope galactose-α-1,3-galactose (α-Gal) was first described in oncologic patients treated with cetuximab. An association with tick bites and parasitosis is suspected. We report on a healthy patient who developed sudden anaphylactic reactions after the ingestion of meat.