The sweet-home project: audio technology in smart homes to improve well-being and reliance.

The Sweet-Home project aims at providing audio-based interaction technology that lets the user have full control over their home environment, at detecting distress situations and at easing the social inclusion of the elderly and frail population. This paper presents an overview of the project focusing on the multimodal sound corpus acquisition and labelling and on the investigated techniques for speech and sound recognition. The user study and the recognition performances show the interest of this audio technology.

CycSim--an online tool for exploring and experimenting with genome-scale metabolic models.

Summary: CycSim is a web application dedicated to in silico experiments with genome-scale metabolic models coupled to the exploration of knowledge from BioCyc and KEGG. Specifically, CycSim supports the design of knockout experiments: simulation of growth phenotypes of single or multiple gene deletions mutants on specified media, comparison of these predictions with experimental phenotypes and direct visualization of both on metabolic maps. The web interface is designed for simplicity, putting constraint-based modelling techniques within easier reach of biologists.

Iterative reconstruction of a global metabolic model of Acinetobacter baylyi ADP1 using high-throughput growth phenotype and gene essentiality data.

Background: Genome-scale metabolic models are powerful tools to study global properties of metabolic networks. They provide a way to integrate various types of biological information in a single framework, providing a structured representation of available knowledge on the metabolism of the respective species.

Results: We reconstructed a constraint-based metabolic model of Acinetobacter baylyi ADP1, a soil bacterium of interest for environmental and biotechnological applications with large-spectrum biodegradation capabilities.

Cyclone: java-based querying and computing with Pathway/Genome databases.

Unlabelled: Cyclone aims at facilitating the use of BioCyc, a collection of Pathway/Genome Databases (PGDBs). Cyclone provides a fully extensible Java Object API to analyze and visualize these data. Cyclone can read and write PGDBs, and can write its own data in the CycloneML format.

Model of interactions in biology and application to heterogeneous network in yeast.

A major challenge for bioinformatics and theoretical biology is to build and analyse a unified model of biological knowledge resulting from high-throughput experiment data. Former work analyzed heterogeneous data (protein-protein interactions, genetic regulation, metabolism, synexpression) by modelling them by graphs. These models are unable to represent the qualitative dynamics of the reactions or to model the n-ary interactions.