Publications by authors named "S Slavov"
Routine Detection of Viruses Through Metagenomics: Where Do We Stand?
Am J Trop Med Hyg
December 2024
Serum fibronectin levels in malignant and benign endometrial diseases.
Prz Menopauzalny
September 2024
Introduction: Endometrial cancer is currently the most common malignancy of the female reproductive system. The significance of the disease is determined by the search for additional biomarkers with the aim to optimize earlier diagnosis and to help for timely treatment. The objective of this study was to assess the serum levels of fibronectin (FN) in patients with malignant endometrial pathology and to compare them with patients with benign pathology and healthy women.
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- * An analysis of viral genome sequences combined with epidemiological data revealed that Italy experienced four significant epidemic waves between 2021 and 2023, marked by reduced fatalities and influenced by variants like Alpha, Delta, and Omicron.
- * This study emphasizes the need for adaptable public health strategies and continuous genomic surveillance to effectively track virus evolution and prepare for potential future outbreaks.
Article Synopsis
- Human Pegivirus-1 (HPgV-1) is commonly found in humans but its effects on pediatric cancer patients with febrile neutropenia (FN) are not well-studied.
- In a study analyzing 30 children, it was found that 23.3% had detectable HPgV-1 RNA, with slightly higher rates in those with FN (26.7%).
- The predominant strain in the samples was identified as HPgV-1 genotype 2, prompting further research into its potential impact on FN and the health of immunocompromised patients.
Unveiling viral pathogens in acute respiratory disease: Insights from viral metagenomics in patients from the State of Alagoas, Brazil.
Gabriel Montenegro de Campos Hazerral de Oliveira Santos Alex Ranieri Jerônimo Lima Anderson Brandão Leite Gabriela Ribeiro Svetoslav Nanev Slavov
PLoS Negl Trop Dis
September 2024
Article Synopsis
- Respiratory illnesses caused by viral infections affect all age groups but are challenging to diagnose due to overlapping symptoms and incomplete local diagnostic panels.
- A metagenomic study of 66 nasopharyngeal swab samples from patients with acute respiratory issues revealed significant undetected viruses, like rhinoviruses and enterovirus D68, as well as other notable viruses such as human herpesvirus and human parvovirus B19.
- The findings highlight the critical role of viral metagenomics in uncovering overlooked viruses, which could inform public health strategies to improve diagnostics and patient care.