Publications by authors named "S Sivabalan"

Unlabelled: During microbial surveillance of the Mars 2020 spacecraft assembly facility, two novel bacterial strains, potentially capable of producing lasso peptides, were identified. Characterization using a polyphasic taxonomic approach, whole-genome sequencing and phylogenomic analyses revealed a close genetic relationship among two strains from Mars 2020 cleanroom floors (179-C4-2-HS, 179-J1A1-HS), one strain from the Agave plant (AT2.8), and another strain from wheat-associated soil (V4I25).

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Microorganisms are ubiquitous in nature and form complex community networks to survive in various environments. This community structure depends on numerous factors like nutrient availability, abiotic factors like temperature and pH as well as microbial composition. Categorising accessible biomes according to their habitats would help in understanding the complexity of the environment-specific communities.

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Article Synopsis
  • Allergic bronchopulmonary aspergillosis (ABPA) is a serious condition that can complicate asthma in children, prompting the need for evidence-based management guidelines developed by the Indian Academy of Pediatrics.
  • The Evidence Based Guideline Development Group (EBGDG) identified seven key clinical questions, gathering and analyzing existing evidence to formulate recommendations regarding the investigation and treatment of ABPA in asthmatic children.
  • Key recommendations include investigating children with poorly controlled asthma for ABPA, favoring low-dose steroid therapy, avoiding oral steroids beyond 16 weeks, and being cautious with antifungal choices, while noting that no solid evidence supports pulse steroid therapy over conventional methods.
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