Prevalence of use of nonpharmacological methods of pain relief among patients following onco surgeries - A prospective, observational cohort study from a single center.

Background And Aims: For the aggressive treatment of postoperative pain, nonpharmacological methods (NPMs) are gaining importance complementary to routine multimodal pain management. The primary aim of the study was to assess the incidence of use of NPMs in our hospital. Secondary objectives were to correlate the pain scores, patient satisfaction, and percentage of time the patient was in severe pain within 72 h postsurgery with the use of NPMs when in pain/not in pain.

Phenotypic evolution of SARS-CoV-2 spike during the COVID-19 pandemic.

SARS-CoV-2 variants are mainly defined by mutations in their spike. It is therefore critical to understand how the evolutionary trajectories of spike affect virus phenotypes. So far, it has been challenging to comprehensively compare the many spikes that emerged during the pandemic in a single experimental platform.

Distinct Charge and Spin Recovery Dynamics in a Photoexcited Mott Insulator.

Pump-probe response of the spin-orbit coupled Mott insulator Sr_{2}IrO_{4} reveals a rapid creation of low-energy optical weight and suppression of three-dimensional magnetic order on laser pumping. Postpump there is a quick reduction of the optical weight but a very slow recovery of the magnetic order-the difference is attributed to weak interlayer exchange in Sr_{2}IrO_{4} delaying the recovery of three-dimensional magnetic order. We suggest that the effect has a very different and more fundamental origin.

Protein translation can fluidize bacterial cytoplasm.

The cytoplasm of bacterial cells is densely packed with highly polydisperse macromolecules that exhibit size-dependent glassy dynamics. Recent research has revealed that metabolic activities in living cells can counteract the glassy nature of these macromolecules, allowing the cell to maintain critical fluidity for its growth and function. While it has been proposed that the crowded cytoplasm is responsible for this glassy behavior, a detailed analysis of the size-dependent nature of the glassy dynamics and an explanation for how cellular activity induces its fluidization remains elusive.

Auditory System Abnormalities in Early Graying of Hair: A Cross-Sectional Study.

Background: Melanocytes in the hair and melanocytes in the stria vascularis of the inner ear have common origins. Many congenital and acquired disorders of cutaneous pigmentation have auditory abnormalities. There is a paucity of studies on the auditory associations of early graying.