Publications by authors named "S Silvera"
Article Synopsis
- * GSK3 inhibition alone or combined with aerobic exercise leads to improvements in muscle strength, endurance, insulin sensitivity, and overall metabolism in mdx mice.
- * This strategy also enhances bone health, suggesting that targeting GSK3 may offer a new treatment approach for DMD patients, contrasting with current glucocorticoid treatments that pose additional health risks.
Sacrocolpopexy and rectopexy are commonly used surgical options for treatment of patients with pelvic organ and rectal prolapse, respectively. These procedures involve surgical fixation of the vaginal vault or the rectum to the sacral promontory with mesh material and can be performed independently of each other or in a combined fashion and by using an open abdominal approach or laparoscopy with or without robotic assistance. Radiologists can be particularly helpful in cases where patients' surgical histories are unclear by identifying normal sacrocolpopexy or rectopexy mesh material and any associated complications.
View Article and Find Full Text PDFSarco(endo)plasmic reticulum Ca-ATPase (SERCA) uncoupling in skeletal muscle and mitochondrial uncoupling via uncoupling protein 1 (UCP1) in brown/beige adipose tissue are two mechanisms implicated in energy expenditure. Here, we investigated the effects of glycogen synthase kinase 3 (GSK3) inhibition via lithium chloride (LiCl) treatment on SERCA uncoupling in skeletal muscle and UCP1 expression in adipose. C2C12 and 3T3-L1 cells treated with LiCl had increased SERCA uncoupling and UCP1 protein levels, respectively, ultimately raising cellular respiration; however, this was only observed when LiCl treatment occurred throughout differentiation.
View Article and Find Full Text PDFTo assess perceptions of university institutional climate related to sexual violence and whether these differed by race/ethnicity. Matriculated undergraduates 18 ( = 1028). Students were invited via campus email to participate in an online survey.
View Article and Find Full Text PDFObjectives: Although much research has been conducted on knowledge and awareness of the connection between human papillomavirus (HPV) and cervical cancer risk among university students, few studies have examined these associations among low-income populations. We examined knowledge of HPV and cervical cancer risk among racially and ethnically diverse low-income women.
Methods: We used a cross-sectional study design to recruit and interview 476 low-income women in New Jersey from November 1, 2013, through February 28, 2016.