Relationship between skin blood flow regulation mechanisms and vascular endothelial growth factor in patients with metabolic syndrome.

The focus of this paper is the determination of endothelial dysfunction in patients with metabolic syndrome (MetS) and the establishment of a relationship between the traditional biomarkers of endothelial dysfunction and the vascular tone regulation indices obtained from indirect cold tests in MetS patients. Our investigation was conducted on 30 patients aged 45.5±9 years.

[The biomarkers of systemic inflammation and polymorphism of genes TNFα-308GA (rs 1800629) and IL6-174CG (rs 1800795) in evaluation of functional condition of kidneys in patients with obesity.].

The purpose of study was to analyze relationships between polymorphism of genes TNFα (-308GA) and IL6 (-174CG) and functional condition of kidneys in patients with various phenotype of obesity. The sampling included 170 individuals aged from 25 to 55 years (90 patients with obesity, metabolic disorders and arterial hypertension - group of "complicated obesity", 50 individuals with obesity without metabolic complications - group of "metabolically healthy obesity" and 30 individuals with arterial hypertension without obesity). The analysis was applied to clinical biochemical indices, levels of TNFα, IL-6 in blood serum and urine, microalbuminuria, collagen IV in urine, polymorphism of genes TNFα (-308GA) and IL6 (-174CG).

[Biological value and storage stability of cultured milk products intended for cosmonaut nutrition].

Freeze-dried culture milk products--yoghurt with sugar, yoghurt with fruits and berries, acidophilic paste--were examined in the course of storage. The optimal time of their storage was determined, high biological value of protein and good viability of lactic-acid microflora were demonstrated. These products are recommended to be incorporated into space diets.