Publications by authors named "S Shirali"

Article Synopsis
  • The study investigates the role of complement dysregulation in age-related macular degeneration (AMD) and a specific variant of complement factor H (CFH) in early-onset macular drusen (EOMD).
  • Researchers identified a new CFH variant in a family with EOMD and used patient-derived stem cells to analyze the effects of CFH and factor H-like protein 1 (FHL-1) on complement activity.
  • The CFH variant led to reduced expression of CFH and FHL-1 and increased complement activation in retinal cells, providing evidence that CFH deficiencies contribute to EOMD development.
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Cutaneous leishmaniasis (CL) is a vector-borne disease widely distributed in tropical and subtropical areas of North and South America, Europe, Asia, and Africa. Considering the increasing number of CL cases in recent years and the fact that no study has been conducted to identify CL fauna and vectors in Alborz province, this study was carried out to identify sand flies and CL vectors in this region. Sand flies were collected from August to October 2021 from plain and mountainous indoor and outdoor areas of the region using sticky paper traps and were detected morphologically.

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Background: Sarcocystosis is a zoonotic disease worldwide caused by spp., some of these species can show clinical and subclinical manifestations, resulting in financial losses. Our study was performed for identifying sp.

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Fascioliasis is an emerging and important food and water-borne disease in human communities which has become one of the most important health challenges in countries, like Iran. It causes weight loss, a decrease in feed conversion ratio as well as milk and meat production, and also reduces fertility in animals the prevalence of fasciolosis is increasing in some regions of the world due to various factors. Different methods have been used for the detection of Fasciola hepatica in animals.

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