Publications by authors named "S Shinden"

Objective: Febrile neutropenia (FN) is the most serious toxicity in patients with head and neck squamous cell carcinoma (HNSCC) treated with induction chemotherapy (IC). Although it is well-known that sarcopenia is a risk factor for severe toxicity of (chemo)radiotherapy, the data on the association between sarcopenia and FN during IC in HNSCC patients is rare. This study determined the impact of sarcopenia on FN during IC.

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Measurement of thyroglobulin in fine-needle aspirates (FNA-Tg) is useful for the diagnosis of lymph node metastasis in thyroid carcinoma; however, the cutoff value remains unclear, particularly for the differential diagnosis of neck masses. To evaluate the cutoff value of FNA-Tg, we conducted a retrospective study of patients with neck masses outside the thyroid who pre-operatively underwent both FNAC and FNA-Tg, followed by pathological examination at our hospital from October 2015 to September 2020. The cutoff value of FNA-Tg was calculated using the receiver operating characteristic curve.

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Article Synopsis
  • This study evaluates the combined impact of sarcopenia (muscle loss) and systemic inflammation on survival in patients with head and neck squamous cell cancer (HNSCC), revealing that this combination is a better prognostic marker than sarcopenia alone.
  • Researchers analyzed medical records of 100 HNSCC patients, finding that those with sarcopenia exhibited worse overall and progression-free survival, particularly when low lymphocyte/monocyte ratio (LMR) was present.
  • The results suggest that using sarcopenia alongside LMR can effectively identify patients at greater risk of poor outcomes, enhancing prognosis.
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  • The study investigated if brain imaging could predict cochlear implant (CI) outcomes for patients with severe to profound hearing loss before surgery.
  • A total of 64 patients, including those with congenital and acquired hearing loss, underwent preoperative MRI analysis to assess cortical thickness in specific brain regions.
  • Results indicated that certain brain areas, especially in the right and left hemispheres, correlated with better speech discrimination, particularly in patients with acquired hearing loss, suggesting that brain structure could guide clinical decisions for CI.
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Atherosclerosis is reported to be a risk factor for the severity of idiopathic sudden sensorineural hearing loss (ISSNHL). We evaluated the hypothesis that atherosclerosis affects the hearing thresholds of both the affected and healthy sides of ISSNHL patients. We conducted multivariate analyses on retrospectively collected data of patients with ISSNHL (N = 762) to evaluate the relationship between known factors linked to atherosclerosis and hearing thresholds on affected and healthy sides and whether these factors are prognostic for hearing recovery.

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