A silyl porphyrin derivative conjugated with 6-deoxy-6-sulfo-α-d-glucopyranose functions as an efficient photosensitizer for photodynamic therapy.

We synthesized a new silyl porphyrin derivative conjugated with 6-deoxy-6-sulfo-α-d-glucopyranose (SGlc). Conjugation with SGlc improved A549 cellular uptake without significant changes in the photophysical and photochemical properties and subcellular localization. This improved cellular uptake led to enhanced photodynamic activity.

Alternative Bypass Technique Using Radial Artery Graft between V3 Segment of Vertebral Artery and Middle Cerebral Artery: Technical Note.

Background:  There are some cases where a radial artery (RA) graft is needed for a high-flow extracranial to intracranial (EC-IC) bypass as the external carotid artery (ECA) cannot be utilized as a donor artery. In this report, we describe two cases of extracranial vertebral artery (VA) to middle cerebral artery (MCA) high-flow bypass using an RA graft with an artificial vessel as an alternative bypass technique.

Methods:  The patient was placed supine with a head rotation of 80 degrees.

Real-time transmission of geometrically-shaped signals using a software-defined GPU-based optical receiver.

A software-defined optical receiver is implemented on an off-the-shelf commercial graphics processing unit (GPU). The receiver provides real-time signal processing functionality to process 1 GBaud minimum phase (MP) 4-, 8-, 16-, 32-, 64-, 128-ary quadrature amplitude modulation (QAM) as well as geometrically shaped (GS) 8- and 128-QAM signals using Kramers-Kronig (KK) coherent detection. Experimental validation of this receiver over a 91 km field-deployed optical fiber link between two Tokyo locations is shown with detailed optical signal-to-noise ratio (OSNR) investigations.