Am J Physiol Gastrointest Liver Physiol
January 2025
Appetite, as the internal drive for food intake, is often dysregulated in a broad spectrum of conditions associated with over- and under-nutrition across the lifespan. Appetite regulation is a complex, integrative process comprising psychological and behavioral events, peripheral and metabolic inputs, and central neurotransmitter and metabolic interactions. The microbiota-gut-brain axis has emerged as a critical mediator of multiple physiological processes, including energy metabolism, brain function, and behavior.
View Article and Find Full Text PDFIn the present work, a diazonium salt is prepared by a diazonium reaction of sulfamerazine in the presence of aqueous hydrochloric acid and sodium nitrate. Structural confirmation of azo compounds synthesize is achieved by mass spectrometry, infrared spectroscopy, and H, C nuclear magnetic resonance. The sample geometry is derived using Density Functional Theory (DFT) and DT-DFT applied to the basis set B3LYPL6-311 + G(d,p).
View Article and Find Full Text PDFThe mechanisms through which systemic inflammation exerts its effect on the central nervous system (CNS) are still not completely understood. Exosomes are small (30 to 100 nm) membrane-bound extracellular vesicles released by most of the mammalian cells. Exosomes play a vital role in cell-to-cell communication.
View Article and Find Full Text PDFArch Razi Inst
April 2024
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