Publications by authors named "S Shayan Mousavi Masouleh"

Recent evidence has proved that thymoquinone as a natural polyphenol has great anticancer and anti-proliferative effects in cancer cells. In this study, we aimed to examine the effects of thymoquinone on increasing cisplatin-induced apoptosis human oral squamous cell carcinoma cells and its underlying molecular mechanisms. SCC-25 cancer cells treated by thymoquinone and cisplatin with different concentrations.

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Background: Around 15% of couples of childbearing age suffer from infertility; in 50% of these cases, the male factor is present. In this study, we investigated the association between anti-ODF2 autoantibody existence and the DNA fragmentation and apoptosis of sperm in oligozoospermia men.

Material And Methods: 35 fertile men and 57 oligozoospermia men are enrolled in this study as control and case groups, respectively.

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Introduction: Hippocampal local and network dysfunction is the hallmark of Alzheimer's disease (AD).

Methods: We characterized the spatial patterns of hippocampus differentiation based on brain co-metabolism in healthy elderly participants and demonstrated their relevance to study local metabolic changes and associated dysfunction in pathological aging.

Results: The hippocampus can be differentiated into anterior/posterior and dorsal cornu ammonis (CA)/ventral (subiculum) subregions.

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Article Synopsis
  • The study explores how the brain's structure influences its necessary functions for cognition and behavior, focusing on the connection between structural organization and cognitive flexibility.
  • It finds that in humans, the strongest structure-function connections are in unimodal cortex areas, while transmodal regions show less alignment with genetic factors, which is also observed in macaques but with some differences in association cortices.
  • The research indicates that areas with less genetic influence are tied to advanced cognitive functions, suggesting that evolutionary changes in brain structure and function may facilitate complex cognitive abilities.
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Oral lichen planus (OLP) is a premalignant disease with unknown etiology. It has been demonstrated that inflammation and immune activation play a central role in the pathogenesis of OLP. Various cellular and molecular mechanisms are involved in the pathogenesis of OLP.

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