Phytoconstituents of as a potential adjunct in the treatment of anxiety disorders: In vivo and in silico approaches.

Traditional plants have played a vital role in civilization and medicine throughout history. , a plant used in South Asian traditional medicine, has various medicinal applications but limited research on its impact on the central nervous system (CNS). This study analyzed the methanolic leaf extract of (MECE) for secondary metabolites and conducted experiments to evaluate the sedative, and anxiolytic effect of MECE on a mice model.

Isolation, characterization, and analysis of pure compounds from leaf extract for antibacterial, antidiabetic, cytotoxicity and phytotoxicity.

This research aims to isolate, characterize, and analyze pure compounds from leaf extract to investigate its antibacterial, antidiabetic, cytotoxic, and phytotoxic effects. Fresh leaves were collected, dried, and subjected to methanol extraction to obtain a crude extract. From the petroleum ether fraction (PEF) of this extract, three fractions-designated LM1, LM2, and LM3-were prepared using column chromatography.

Prenatal exposure to antibiotics and the risk of orofacial clefts: a protocol for a systematic review and meta-analysis.

Introduction: Orofacial clefts (OFCs), including cleft lip, cleft palate and combined cleft lip and palate, are among the most common craniofacial malformations in newborns and present significant healthcare challenges. Emerging evidence has raised concerns regarding the potential impact of prenatal exposure to antibiotics on fetal development. Antibiotics prescribed during pregnancy-particularly those that cross the placental barrier-may pose teratogenic risks.