Clinical epidemiology of pulmonary aspergillosis in hospitalized patients and contribution of Cyp51A, Yap1, and Cdr1B mutations to voriconazole resistance in etiologic Aspergillus species.

Pulmonary aspergillosis is a life-threatening fungal infection with worldwide distribution. In the present study, clinical epidemiology of pulmonary aspergillosis and antifungal susceptibility of etiologic Aspergillus species were evaluated in one-hundred fifty patients with special focus on the frequency of voriconazole resistance. All the cases were confirmed by the clinical pictures, laboratory findings, and isolation of etiologic Aspergillus species which belonged to two major species, i.

Molecular discrimination and antifungal susceptibility profile of cryptic complex species isolated from patients in Iran.

Background And Objectives: complex species are well known as the main cause of candidiasis, particularly among susceptible individuals. In this study, we report the genetic diversity of spp. and the antifungal susceptibility pattern of the cryptic complex isolates in Kerman, Iran.

Phylogenetic relationship of species isolated from keratitis using and gene sequences.

Background And Objectives: species are known to be one of the common causes of keratitis. This study was conducted to identify spp. causing keratitis and to investigate their genetic diversity using and gene sequences.

Local Administration of Sodium Bicarbonate for Preventing COVID-19 Associated Mucormycosis.

Background: One important complication of the coronavirus disease 2019 (COVID-19) is COVID Associated Mucormycosis (CAM), especially in patients with conditions such as diabetes and in immunosuppressed patients. Systemic acidosis, hyperglycemia, and other biochemical factors such as free iron and β-hydroxybutyrate (BHB) can play a role in this complication.

Materials And Methods: was isolated from a patient at Masih Daneshvari Hospital microbiology laboratory and sub-cultured on the Potato Dextrose Agar (PDA) for 48 hours at 37 °C.

Delayed post-pneumonectomy empyema necessitans caused by : An unusual report.

Post-pneumonectomy empyema (PPE), with or without bronchopleural fistula, is a challenging and serious entity with significant mortality and morbidity. PPE is usually caused by bacteria such as staphylococci, streptococci and also gram-negative rods. Among fungal pathogens, species is a very rare cause of this entity.