Basic Science and Pathogenesis.

Background: In previous studies, we found that quetiapine activates the AKT signaling which further inhibits the action of GSK3β. Quetiapine has been reported to possess neuroprotective potential in schizophrenia and other neurodegenerative models.

Method: On day 1 and 3, rats received bilateral intracerebroventricular (i.

Probing the Electric Double-Layer Capacitance to Understand the Reaction Environment in Conditions of Electrochemical Amination of Acetone.

To elucidate interfacial dynamics during electrocatalytic reactions, it is crucial to understand the adsorption behavior of organic molecules on catalytic electrodes within the electric double layer (EDL). However, the EDL structure in aqueous environments remains intricate when it comes to the electrochemical amination of acetone, using methylamine as a nitrogen source. Specifically, the interactions of acetone and methylamine with the copper electrode in water remain unclear, posing challenges in the prediction and optimization of reaction outcomes.

Induction of PD-1 and CD44 in CD4 T cells by circulatory extracellular vesicles from severe dengue patients drives endothelial damage via the NF-kB signaling pathway.

Extracellular vesicles (EVs) emerged as critical contributors to the pathogenesis of vascular endothelial barrier dysfunction during the inflammatory response to infection. However, the contribution of circulating EVs to modifying endothelial function during dengue virus infection remains unclear. In this study, we showed that severe dengue patients' plasma-derived EV (SD-EV) were found to carry elevated levels of different protein cargos, e.

Synchronous primary tumors amd distant metastasis detected on F-FDG PET in patients with head and neck carcinoma.

Objectives: F-FDG PET/CT has been used to characterize the primary lesion and staging in head and neck cancers (HNC). However, prior studies for detecting distant metastasis and synchronous tumors are sparse, especially in Indian context. To investigate the frequency and distribution of head and neck carcinomas, distant metastases and synchronous malignancies detected in HNC in a north Indian population.

Examining nursing students' awareness of various medical errors during clinical internships to enhance patient safety: A multi-center cross-sectional study.

Background: Patient safety is a global concern within health facilities, primarily attributed to medical errors, constituting a significant global public health issue. Patients experiencing medication errors face serious problems, with increasing mortality rates and escalating hospital costs.

Aim: The study aims to examine nursing students' awareness of various medical errors during their clinical internships at Al- Ahsa, identifying types of errors to enhance patient safety.