Synthesis, modification, characterization, and in vitro evaluation of chitosan-hyaluronic acid coated MIL-100 (Fe) nanoparticles for methotrexate delivery in rheumatoid arthritis.

Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by inflammation of the joints, leading to pain, swelling, and potential joint destruction. Effective management of RA is crucial to improve patients' quality of life and prevent long-term disability. Methotrexate (MTX) is a widely used disease-modifying antirheumatic drug (DMARD) that has shown efficacy in treating RA.

Efficient CO adsorption by deoiled flaxseed hydrochar.

This study optimizes CO adsorption using hydrochar from de-oiled flaxseed (FDOP), a waste byproduct of the oil extraction industry, through hydrothermal carbonization (HTC). The aim is to enhance CO capture sustainably and cost-effectively. Using Response Surface Methodology (RSM), in optimal conditions achieved 1153.

Nanoporous Metatitanic acid on γ-AlO aerogel for higher CO adsorption capacity and lower energy consumption.

Carbon dioxide capture has become an important issue in reducing atmospheric heat these days. In this study, adsorption of carbon dioxide by aerogel Gamma Alumina-Metatitanic Acid has been investigated and optimized. Morphological and structural analyses such as BET, FESEM, FT-IR, and XRD have also been conducted.

Improving CO adsorption efficiency of an amine-modified MOF-808 through the synthesis of its graphene oxide composites.

This research developed a novel composite of MOF-NH and graphene oxide (GO) for enhanced CO capture. Employing the response surface methodology-central composite design (RSM-CCD) for experiments design, various MOF-NH/GO samples with GO loadings from 0 to 30 wt% were synthesized. The results of SEM, XRD, EDS, and BET analysis revealed that the materials maintained their MOF crystal structure, confirmed by X-ray diffraction, and exhibited unique texture, high porosity, and oxygen-enriched surface chemistry.

RadioLabeling of the Mutant form of Anti-PlGF Nanobody by Tc-Tricarbonyl.

Background: Molecular imaging is a highly effective method for diagnosing cancer and evaluating treatment. A molecular tracer often consists of two segments: A targeting segment, which can be antibodies, antibody fragments, or VHH (nanobody), and a detection segment, such as radioisotopes. The small size of VHH allows for excellent tissue penetration and fast clearance, resulting in minimal nonspecific background, which makes them appealing for use as imaging agents.