Publications by authors named "S Sedlis"
Randomized clinical trials have not demonstrated a survival benefit with percutaneous coronary intervention in stable ischemic heart disease (SIHD). We evaluated the generalizability of the COURAGE (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation) trial findings to the broader population of veterans with SIHD. Veterans who underwent coronary angiography between 2005 and 2013 for SIHD were identified from the Veterans Affairs Clinical Assessment, Reporting and Tracking Program (VA CART).
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- The study analyzed the association between Canadian Cardiovascular Society (CCS) angina severity classification and outcomes like mortality and healthcare use in US veterans with stable angina from 2006 to 2013.
- A total of 14,216 veterans, primarily older white males, had their CCS classifications extracted using natural language processing, showing varying mortality rates across CCS classes I to IV over a median follow-up of 3.4 years.
- Veterans classified in higher CCS classes (III and IV) had significantly higher rates of all-cause mortality and healthcare utilization compared to those in CCS class I, indicating the importance of CCS classification in predicting patient outcomes.
Background: Individual risk factor control improves survival in patients with stable ischemic heart disease (SIHD). It is uncertain if multiple risk factor control further extends survival.
Objectives: This study determined whether a greater number of risk factors at goal predicted improved survival in SIHD patients.
Background: Percutaneous coronary intervention (PCI) is a therapy to reduce angina and improve quality of life in patients with stable ischemic heart disease. However, it is unclear whether the quality of life after PCI is more dependent on the PCI or other patient-related factors. To address this question, we created models to predict angina and quality of life 1 year after PCI and medical therapy.
View Article and Find Full Text PDFBackground: Type 2 myocardial infarction (MI) is defined by a rise and fall of cardiac biomarkers and evidence of ischemia without unstable coronary artery disease (CAD) because of a mismatch in myocardial oxygen supply and demand. Myocardial injury is similar but does not fulfill the clinical criteria for MI. There is uncertainty in terms of the clinical characteristics, management, and outcomes of type 2 MI and myocardial injury in comparison with type 1 MI.
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