Körperdysmorphe Symptome, soziale Anpassung und Motivation zu psychotherapeutischer Beratung bei ambulanten dermatologischen Patienten.

Hintergrund Und Ziele: Die Dermatologie ist zunehmend mit Patienten konfrontiert, die unter einer körperdysmorphen Störung (KDS) leiden. Die KDS ist gekennzeichnet durch die übermäßige Beschäftigung mit einem oder mehreren wahrgenommenen Defekten oder Makeln in der äußeren Erscheinung, die für andere nicht oder allenfalls minimal erkennbar sind. Bislang gibt es nur wenige Prävalenzstudien bei KDS im ambulanten dermatologischen Setting.

Body dysmorphic concerns, social adaptation, and motivation for psychotherapeutic support in dermatological outpatients.

Background And Objectives: Dermatologists are increasingly confronted with patients affected by body dysmorphic disorder (BDD). BDD is characterized by excessive preoccupation with one or more perceived defect(s) or flaw(s) in physical appearance which are not observable or appear slight to others. So far, there have been only few studies examining the prevalence of BDD in dermatological outpatients.

Assessment of anti-inflammatory activity of Poria cocos in sodium lauryl sulphate-induced irritant contact dermatitis.

Objective: In the present study, we evaluated the anti-inflammatory activity of Poria cocos (PoCo) on experimentally induced irritant contact dermatitis (ICD) in a repeated sodium lauryl sulphate (SLS) irritation model.

Methods: The anti-irritative effect of PoCo was evaluated with a visual score and quantified by non-invasive bioengineering methods, namely chromametry and transepidermal water loss. Three concentrations of PoCo in base cream DAC (amphiphilic emollient; German pharmacopoeia) were tested in a 4-day repetitive irritation test using SLS.

Induction of a hardening phenomenon by repeated application of SLS: analysis of lipid changes in the stratum corneum.

Adaptation of the skin to repeated influence of exogenous irritants is called the hardening phenomenon. We investigated the stratum corneum lipid composition before and after induction of a hardening phenomenon. Irritant contact dermatitis was induced in 23 non-atopic volunteers by repeated occlusive application of 0.