Publications by authors named "S Schirmer"

Article Synopsis
  • - Sacubitril/valsartan significantly improves outcomes in patients with chronic heart failure and reduced ejection fraction, enhancing left ventricular (LV) function over six months of treatment.
  • - Key improvements were observed, including increased LV contractility (Ees), decreased afterload (Ea), and enhanced ventricular-arterial coupling ratio (Ea/Ees), along with a notable increase in left ventricular ejection fraction (LVEF) from 33% to 43%.
  • - The study found positive correlations between changes in LVEF and LV contractility, as well as between NT-proBNP levels and left ventricular end-diastolic pressure (LVEDP), suggesting these factors play a role in the treatment's effectiveness
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Patients with chronic kidney disease (CKD) have a high incidence and prevalence of atrial fibrillation (AF). While general treatment strategies for AF may largely be transferred to patients with mild to moderate CKD, patients with advanced CKD-particularly hemodialysis (HD) patients-with AF pose substantial therapeutical challenges to cardiologists and nephrologists. The arguably greatest dilemma is the very limited evidence on appropriate strategies for prevention of stroke and systemic embolism in HD patients with AF, since the risk for both thromboembolic events without oral anticoagulation and severe bleeding events with oral anticoagulation are substantially increased in advanced CKD, compared with the general population.

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Article Synopsis
  • Risk assessment for patients with cardiovascular diseases prior to noncardiac surgery is crucial due to the complexity of these cases and the need for multidisciplinary approaches.
  • The assessment relies on factors like the type of surgery, the patient's cardiovascular health, and age, with preoperative consultations being less intensive when operation risks are low.
  • Key evaluation tools include monitoring symptoms, exercise tolerance, and cardiac biomarkers like NT-proBNP and troponin, while existing cardiovascular medications should be maintained during surgery without new drugs being started.
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Understanding how organisms are coping with major changes imposed by urban intensification is a complex task. In fact, our understanding of the impacts of urbanization on biodiversity is scarce in the global south compared to the north. In this study, we evaluated how bird communities are affected by impact of urban intensification in a tropical city.

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Habitat loss and degradation are key drivers of the current biodiversity crisis. Most research focuses on the question of which traits allow species to persist in degraded habitats. We asked whether a species' trophic position or niche width influences the resilience of species in degraded habitats and to what extent habitat degradation affects trophic interactions between species.

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