Comparison of Concentration- and Homology-Dependent Effects of the Proinflammatory Cytokine Interleukin-1β (IL-1β) in a Bovine Chondrocyte Inflammation Model.

Inflammation models with the proinflammatory cytokine interleukin-1β (IL-1β) are widely used in the in vitro investigation of new therapeutic approaches for osteoarthritis (OA). The aim of this study was to systematically analyze the influence of IL-1β in a 3D chondral pellet culture model. Bovine articular chondrocytes were cultured to passage 3 and then placed in pellet culture.

Dynamic rasterstereography improves the detection of movement delays and dynamic asymmetries in the scapulothoracic kinematic of healthy subjects.

Purpose: Assessing scapulothoracic kinematics typically involves visually observing patients during movement, which has limited inter- and intraobserver reliability. Dynamic rasterstereography (DRS) records, measures and visualizes surface structures in real time, using a curvature map to colour-code convex, concave and saddle-shaped structures on the body surface. This study aimed to evaluate the diagnostic efficacy of DRS-assisted observation in identifying dyskinetic scapulothoracic patterns.

Impact of Patient-Specific Hip Joint Geometry on the Morphology of Acetabular Fractures.

: Acetabular fractures continue to pose a major challenge in clinical practice, not least because of the growing geriatric population. While the influence of the force vectors on fracture formation is well established, the impact of anatomical factors on fracture morphology remains poorly understood. The aim of this study was to investigate patient-specific hip joint geometry, identify structural risk factors and correlate these with the resulting fracture patterns.