Publications by authors named "S Schadmand-Fischer"
Article Synopsis
- A 54-year-old woman presented with upper abdominal pressure, difficulty breathing, and swelling, leading to the discovery of pleural effusion, ascites, and an enlarged lymph node, suggestive of ovarian cancer.
- Upon further examination through gynecological sonography, findings confirmed ascites, an ovarian cyst, and peritoneal carcinosis, prompting a staging laparoscopy.
- Biopsies revealed a stage III B-cell lymphoma instead of ovarian cancer, and the patient began successful treatment with R-CHOP chemotherapy, showing stable health six months later.
Adult-onset familial insulinomatosis is a rare disorder with recurrent, severe hypoglycemia caused by multiple insulin-secreting pancreatic tumors. The etiology was unclear until the variant p.Ser64Phe in the transcription factor MAFA, a key coordinator of β-cell insulin secretion, was defined as the cause in two families.
View Article and Find Full Text PDFBackground: Rituximab is a well-established component of treatment regimens for B-cell non-Hodgkin lymphoma. Rituximab binds the CD20 antigen on the surface of B lymphocytes, causing an enhanced clearance of malignant and benign B cells. Thus, rituximab leads to depletion of normal B lymphocytes as well, which can cause substantial immunodeficiency.
View Article and Find Full Text PDF