Publications by authors named "S Sayegh"
Background: Obesity is a chronic disease associated with other associated medical problems, including atherogenic dyslipidemia. Metabolic bariatric surgery (MBS) has been shown to reduce long-term cardiovascular risk (CVR). Anti-ApoA-1 antibodies (AAA1) are independently associated with cardiovascular disease, which remains a major cause of death in individuals with obesity.
View Article and Find Full Text PDFVitamin B12 deficiency is a significant concern among patients with end-stage renal disease undergoing dialysis. However, there hasn't been extensive research conducted on this particular patient group. The reported incidence rates vary widely, ranging from 20% to 90%, reflecting the complexity of its diagnosis.
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- Opioid use in hospitalized patients with chronic kidney disease (CKD) poses safety concerns, especially as the literature on the topic is limited, making it crucial to understand associated complications for patients with impaired kidney function.
- A study analyzed data from the National Inpatient Database from 2016 to 2020, focusing on CKD patients and their experiences with opioid prescriptions, finding that as CKD progressed, the likelihood of uncomplicated opioid use decreased, while complicated use increased in patients with milder CKD stages.
- The results indicate that healthcare providers are more careful when prescribing opioids to those with advanced CKD, leading to fewer prescriptions in this group, while complicated opioid use remains a significant predictor of poisoning, regardless of CKD
Article Synopsis
- Patients with autoimmune diseases, particularly those with inflammatory bowel disease (IBD), face a higher risk of metabolic syndrome (MetS) and cardiovascular disease (CVD), yet research on this is limited.
- A retrospective study examining data from the National Inpatient Sample over five years found that while IBD patients had lower overall prevalence of MetS components compared to non-IBD patients, ulcerative colitis (UC) patients had a higher prevalence than those with Crohn's disease (CD).
- The study demonstrated that higher metabolic scores associated with MetS components were linked to increased risks of acute coronary syndrome and arrhythmias, with significant odds ratios indicating a strong correlation between MetS and heart failure in both IBD types.