Publications by authors named "S Sawicki"
Background: Cannabidiol, which is one of the main cannabinoids present in plants, has been shown to have therapeutic properties, including anti-inflammatory and antioxidant effects that may be useful for treatment of various kidney conditions.
Objectives: This article investigates the effect of long-term cannabidiol (CBD) treatment on changes in the renal transcriptome in a mouse model. The main hypothesis was that systematic CBD treatment would affect gene expression associated with those processes in the kidney.
Article Synopsis
- FDG-PET imaging is a crucial diagnostic tool that aids in differentiating between various neurodegenerative diseases, working alongside other imaging techniques and biomarker studies.
- A systematic review and case series showed how FDG-PET imaging helped clarify uncertain neurocognitive diagnoses in a group of 19 patients, overwhelmingly improving patient care.
- The study found that Dementia with Lewy bodies is often misidentified, highlighting the importance of accurate imaging to prevent misdiagnosis of neurodegenerative conditions.
Cannabidiol (CBD) is abundant in the Cannabis sativa plant and exhibits complex immunomodulatory, anxiolytic, antioxidant, and antiepileptic properties. Several studies suggest that CBD could be used for different purposes in alcohol use disorder (AUD) and alcohol-related injuries to the brain and the liver. In this study, we focused on analyzing transcriptional alterations in human dermal fibroblasts (HDFs) cell line challenged simultaneously with ethanol and CBD as an ethanol-protective agent.
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- Mastitis is a complex inflammatory condition in dairy cattle that is increasingly hard to treat due to antibiotic resistance, prompting research into alternative therapies like mesenchymal stem cells (MSCs).
- This study investigated the effectiveness of allogeneic MSCs derived from bone marrow (BMSC) and adipose tissue (ADSC) for treating mastitis in 39 Polish Holstein-Friesian cows, with various administration methods evaluated.
- Results showed that the use of MSCs led to a significant reduction in bacterial counts and somatic cell count in milk, especially with combined intravenous and intramammary treatments.
Background: Endometrial cancer is the most common gynecologic malignancy found in developed countries. Because therapy can be curative at first, early detection and diagnosis are crucial for successful treatment. Early diagnosis allows patients to avoid radical therapies and offers conservative management options.
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