Publications by authors named "S Savukoski"
Objective: To study ferritin levels, and potential factors influencing them, in women with polycystic ovary syndrome (PCOS), and to investigate potential associations between ferritin levels and other parameters in these women.
Design: Longitudinal general population -based cohort study, including data from both questionnaires and clinical measurements.
Subjects: The study was conducted with data from the participants of the Women's Health Study, including a total of 1918 Finnish women, around 35 years of age.
Article Synopsis
- Research shows that women with premature ovarian insufficiency (POI) are significantly more likely to have a history of severe autoimmune diseases, occurring 2.6 times more often than those without POI.
- The study analyzed data from nearly 4,000 women diagnosed with spontaneous POI, comparing their health outcomes to over 15,000 matched controls, which included tracking autoimmune diagnoses from childhood through 2017.
- Findings indicate that women with POI not only had a higher prevalence of autoimmune disorders prior to their diagnosis but also faced a 2 to 3 times increased risk for these diseases for several years afterward.
The Women's Health Study (WENDY) was conducted to improve insights into women's health and health burden. It provides a unique, comprehensive data source that can be broadly utilised to understand gynaecological symptoms, diseases, and their relation to metabolic and overall health more deeply in a population-based setting. The study was conducted in Finland from May 2020 to October 2022.
View Article and Find Full Text PDFAcute injuries trigger an intense activation of the body's defense mechanisms aiming to limit damage and initiate healing. Among the crucial components of the intravascular immune system, the complement system plays a significant role in traumatic injuries, albeit often negatively. It has been suggested that excessive activation of the complement system, transitioning from a localized and timed response to a systemic one, can lead to a loss of its host-protective characteristics.
View Article and Find Full Text PDFObjective: To study the association between an advanced climacteric status at 46 years of age and current perceived work ability, the consequent 2-year accumulation of disability and unemployment days, and the 7-year incidence of disability pensions.
Methods: Study participants (n = 2,661) were recruited from the Northern Finland Birth Cohort 1966 study's 46-year follow-up in 2012. The participants' perceived work ability was investigated using the Work Ability Score (0-7 = poor vs 8-10 = good), along with potential covariates.