Load sharing behaviour of bio-inspired root pile foundation in cohesionless soil under individual and combined loading conditions.

A bio-inspired root pile foundation is evolved from systematic pile foundation technology. The current investigation focuses on root piles load bearing capacity and behaviour under various loading circumstances, including vertical, lateral, and combined loading. This research aims to investigate behaviour of model piles such as Conventional Pile, 30° Root Pile,45° Root Pile, 60° Root Pile and 90° Root Pile, (hereafter referred as CP, 30° RP, 45° RP, 60° RP and 90° RP) under different monotonic loading conditions with embedded depth (L/D) of 4.

Therapeutic Potential of FTO Demethylase in Metabolism and Disease Pathways.

The crucial involvement of the Fat Mass and Obesity-associated (FTO) protein in both metabolic and non-metabolic diseases has been documented since its discovery. This enzyme, known as FTO, is a demethylase that belongs to the 2-oxoglutarate-dependent nucleic acid demethylases. Its primary function is to target N6-methyladenosine (mA) in RNA, which is crucial in regulating RNA stability, processing, and expression.