Current Scenario in Associating Clinical COVID-19 Biomarkers for Developing Surveillance Platforms.

The novel coronavirus that caused the epidemic and pandemic resulting in the acute respiratory illness known as coronavirus disease 2019 (COVID-19) has plagued the world. This is unlike other coronavirus outbreaks that have occurred in the past, such as Middle East respiratory syndrome (MERS) or severe acute respiratory syndrome (SARS). COVID-19 has spread more quickly and posed special challenges due to the lack of appropriate treatments and vaccines.

Assessing drywell designs for managed aquifer recharge via canals and repurposed wells.

This study explores innovative drywell designs for managed aquifer recharge (MAR) in agricultural settings, focusing on smaller diameter and deeper drywells, including the repurposing of dried or abandoned wells. Numerical simulations assessed the impact of drywell diameter (5-120 cm), depth (15-55 m), screen height, and subsurface heterogeneity on infiltration (I) and recharge (R) volumes over a one-year period under constant head conditions. Results indicate that smaller diameter drywells can effectively infiltrate and recharge significant water volumes.

Prospective observational study of FKRP-related limb-girdle muscular dystrophy R9: A GRASP consortium study.

Objective: Limb-girdle muscular dystrophy R9 (LGMDR9, formerly known as LGMD2I), caused by variants in the fukutin-related protein (FKRP) gene leads to progressive muscle weakness of the shoulder and pelvic limb-girdles and loss of motor function over time. Clinical management and future trial design are improved by determining which standardized clinical outcome assessments (COA) of function are most appropriate to capture disease presentation and progression, informing endpoint selection and enrollment criteria. The purpose of our study was to evaluate the cross-sectional validity and reliability of clinical outcome assessments in patients with FKRP-related LGMDR9 participating in the Genetic Resolution and Assessments Solving Phenotypes in LGMD (GRASP) natural history study.

Triggering the Interplay of sp-sp Carbon-Assisted Sustained Tribofilm via Two-Dimensional Surface Modulation for Exceptional Wear Resistance of Steel Surfaces.

The relentless wear and friction of steel-based moving machinery have created ongoing challenges that hinder their industrial applications. One promising solution is the use of reduced graphene oxide (rGO) as a lubricant due to its excellent mechanical strength and promising tribological properties. However, its tendency to self-agglomerate presents a major hurdle for its practical use.

Nutrition and oral health-related quality of life (OHRQoL) in older adults: a systematic review and meta-analysis.

Background: Understanding the interplay between nutrition and oral health-related quality of life (OHRQoL) in older adults is crucial amidst the global aging population. This systematic review and meta-analysis aimed to explore this association, recognizing the growing prevalence of older individuals and the imperative of addressing their health needs for enhanced well-being.

Materials And Methodology: Following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, relevant studies were identified through electronic database searches and manual screening.