Publications by authors named "S Santhi Sudha"

This study emphasizes the potency of a bacteriocin screened from (MK733983) of ethnomedicinal origin. Antibiofilm analysis with 0.5-3x minimal bacteriocin concentrations with critical and highly prioritized standard microbes such as , , , , , and showed potential biofilm inhibition and eradication of ≥ 5-99%, ≥ 1-86% respectively that correlated with biofilm viable cell-count.

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Tanshinone, a lipophilic component of Salvia miltiorrhiza, is used to treat diseases like atherosclerosis, hypertension, Alzheimer's disease, and diabetes mellitus through its pharmacological activities like anti-inflammatory, anti-oxidant, and anti-tumor. Excessive inflammation is the primary cause of bone diseases such as osteoporosis and rheumatoid arthritis, affecting more than millions of people across the globe. Recently, tanshinone has shown potential benefits against bone diseases by modulating signaling pathways accountable for the proliferation and differentiation of bone cells.

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Article Synopsis
  • Dyskeratosis congenita is a rare genetic disorder that leads to bone marrow failure and is marked by symptoms like nail dystrophy, skin pigmentation issues, and oral leukoplakia.
  • Patients often experience additional complications affecting various body systems, including gastrointestinal and respiratory issues.
  • This report highlights a unique case of a young male with dyskeratosis congenita who developed oral squamous cell carcinoma on the tongue.
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Global energy consumption is expected to reach 911 BTU by the end of 2050 as a result of rapid urbanization and industrialization. Hydrogen is increasingly recognized as a clean and reliable energy vector for decarbonization and defossilization across various sectors. Projections indicate a significant rise in global demand for hydrogen, underscoring the need for sustainable production, efficient storage, and utilization.

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Small cell lung carcinoma (SCLC) is characterized by rapid growth and an aggressive clinical course. Standard therapy regimes have limited effects on disease course; therefore the prognosis of SCLC is poor. In the current study, the frequency of programmed death ligand 1 (PD-L1) expression in SCLC and its correlation with clinico-pathological features were evaluated.

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