This study emphasizes the potency of a bacteriocin screened from (MK733983) of ethnomedicinal origin. Antibiofilm analysis with 0.5-3x minimal bacteriocin concentrations with critical and highly prioritized standard microbes such as , , , , , and showed potential biofilm inhibition and eradication of ≥ 5-99%, ≥ 1-86% respectively that correlated with biofilm viable cell-count.
View Article and Find Full Text PDFNaunyn Schmiedebergs Arch Pharmacol
August 2024
Tanshinone, a lipophilic component of Salvia miltiorrhiza, is used to treat diseases like atherosclerosis, hypertension, Alzheimer's disease, and diabetes mellitus through its pharmacological activities like anti-inflammatory, anti-oxidant, and anti-tumor. Excessive inflammation is the primary cause of bone diseases such as osteoporosis and rheumatoid arthritis, affecting more than millions of people across the globe. Recently, tanshinone has shown potential benefits against bone diseases by modulating signaling pathways accountable for the proliferation and differentiation of bone cells.
View Article and Find Full Text PDFIndian J Pathol Microbiol
July 2024
Global energy consumption is expected to reach 911 BTU by the end of 2050 as a result of rapid urbanization and industrialization. Hydrogen is increasingly recognized as a clean and reliable energy vector for decarbonization and defossilization across various sectors. Projections indicate a significant rise in global demand for hydrogen, underscoring the need for sustainable production, efficient storage, and utilization.
View Article and Find Full Text PDFSmall cell lung carcinoma (SCLC) is characterized by rapid growth and an aggressive clinical course. Standard therapy regimes have limited effects on disease course; therefore the prognosis of SCLC is poor. In the current study, the frequency of programmed death ligand 1 (PD-L1) expression in SCLC and its correlation with clinico-pathological features were evaluated.
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