Publications by authors named "S Sanou"
Cisplatin is a platinum-based compound that is widely used for treating inoperable oral squamous cell carcinoma (OSCC) in Japan; however, resistance to cisplatin presents a challenge and innovative approaches are required. We aimed to investigate the therapeutic potential of targeting the chemokine receptor CXCR4, which is involved in angiogenesis and tumor progression, using the CXCR4 inhibitor AMD3100, in combination with cisplatin. AMD3100 induced necrosis and bleeding in OSCC xenografts by inhibiting angiogenesis.
View Article and Find Full Text PDFBackground: In October 2013, Burkina Faso introduced 13-valent pneumococcal conjugate vaccine (PCV13) into the routine childhood immunization program using 3 primary doses with no booster. Previous pneumococcal carriage studies showed reductions in vaccine-type (VT) carriage in children aged <5 years but not in older age groups.
Methods: We conducted a cross-sectional, age-stratified pneumococcal carriage study among healthy persons aged ≥1 month in Bobo-Dioulasso in March 2020.
Introduction: The town of Djibo in Burkina Faso has been facing a security and humanitarian crisis since 2015. The internally displaced populations who have taken refuge there have several needs, including health care. The establishment of advanced health posts is part of the health-nutrition service delivery strategy adopted to address these needs.
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- - The study investigated the presence of antibiotic-resistant genes (ESBL and carbapenemase) in environmental bacteria from two locations in Bobo-Dioulasso, Burkina Faso, focusing on samples from a hospital and a wastewater treatment facility.
- - Out of 180 bacterial isolates collected, 100% were found to produce extended-spectrum beta-lactamases (ESBLs), while 10% produced carbapenemases, with Klebsiella species being the most commonly identified bacteria.
- - Results indicated a significant prevalence of the bla-CTX-M resistance gene, particularly from hospital effluents, suggesting a critical need for effective treatment systems for hospital waste to manage the spread of antibiotic-resistant bacteria in urban areas.
Introduction: Access to health services is a major challenge in developing countries in general, particularly those affected by insecurity. The availability of sufficient quantity and quality of equitably distributed healthcare workforce is a major obstacle, yet it is an essential pillar of an effective and efficient national health system. Burkina Faso, similar to other countries in the Sahel, has been affected by an unprecedented security crisis that has severely tested the functionality of health facilities and the availability of healthcare workforce.
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