Publications by authors named "S Sankar Banerjee"
Background: There has been limited success of cancer immunotherapies in the treatment of ovarian cancer (OvCa) to date, largely due to the immunosuppressive tumour microenvironment (TME). Tumour-associated macrophages (TAMs) are a major component of both the primary tumour and malignant ascites, promoting tumour growth, angiogenesis, metastasis, chemotherapy resistance and immunosuppression. Differential microRNA (miRNA) profiles have been implicated in the plasticity of TAMs.
View Article and Find Full Text PDFThe proliferation-specific oncogenic transcription factor, FOXM1 is overexpressed in primary and recurrent breast tumors across all breast cancer (BC) subtypes. Intriguingly, FOXM1 overexpression was found to be highest in Triple-negative breast cancer (TNBC), the most aggressive BC with the worst prognosis. However, FOXM1-mediated TNBC pathogenesis is not completely elucidated.
View Article and Find Full Text PDFBackground: Estimation of long-term risk for cardiovascular events using the SMART (Secondary Manifestations of Arterial Disease) risk score can be potentially valuable in devising risk mitigation strategies.
Objectives: The objective of this study was to apply the SMART risk score to compute the risk for major adverse cardiovascular events (MACE) in the U.S.
Article Synopsis
- Polycyclic aromatic hydrocarbons (PAHs) are harmful organic pollutants resulting from incomplete combustion of organic material, posing risks to ecosystems and human health, which necessitates effective remediation methods.
- This study explores the potential of combining nanomaterials with bioremediation techniques, finding that nano-bioremediation improves PAH removal in liquid samples by 18.9% and in soil samples by 14.3% compared to traditional bioremediation alone.
- Various strategies for nano-bioremediation are discussed, including microbial degradation and enzyme enhancement, along with eco-friendly approaches using biogenic nanomaterials to tackle PAH pollution.
The Cumulative Burden of Social Risk Factors and 10-Year Change in Quality of Life.
J Gerontol A Biol Sci Med Sci
December 2024
Background: Social risk factors are linked to adverse health outcomes, but their total impact on long-term quality of life is obscure. We hypothesized that a higher burden of social risk factors is associated with greater decline in quality of life over 10 years.
Methods: We examined associations between social risk factors count and decline >5 points in (i) physical component summary, and (ii) mental component summary scores from the Short Form-12 among Black and White participants in the Reasons for Geographic and Racial Differences in Stroke study (n = 14 401).