Publications by authors named "S Salehpour"

Background: Poor ovarian response and diminished ovarian reserves (DOR) significantly contribute to female infertility. Previous attempts have been made to enhance follicular growth and improve pregnancy outcomes in these participants.

Objective: This study aimed to assess the efficacy of the in vitro drug-free activation technique of the ovarian reservation and in vitro fertilization stimulation cycle outcomes in DOR participants.

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Background And Objective: Autosomal recessive genetic disorders pose significant health challenges in regions where consanguineous marriages are prevalent. The utilization of exome sequencing as a frequently employed methodology has enabled a clear delineation of diagnostic efficacy and mode of inheritance within multiplex consanguineous families. However, these aspects remain less elucidated within simplex families.

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Article Synopsis
  • - This study presents a Delphi consensus from seven Iranian infertility experts focusing on the role of luteinizing hormone (LH) in assisted reproductive technology (ART), aiming to fill a gap in regional consensus documents related to LH supplementation.
  • - The consensus process involved three steps: an initial approval of eight statements, a vote by a 20-member panel, and a revision of one statement that initially lacked agreement, which then achieved an 83% consensus after modification.
  • - The findings emphasize the importance of incorporating expert clinical perspectives into guidelines, particularly to enhance treatment outcomes for patients with deficiencies in follicle-stimulating hormone (FSH) and LH.
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Glycogen storage diseases (GSDs) are a group of rare inherited metabolic disorders characterized by clinical, locus, and allele heterogeneity. This study aims to investigate the phenotype and genotype spectrum of GSDs in a cohort of 14 families from Iran using whole-exome sequencing (WES) and variant analysis. WES was performed on 14 patients clinically suspected of GSDs.

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Article Synopsis
  • Chronic endometritis (CE) is an inflammatory condition that may be linked to intrauterine abnormalities like endometrial polyps and adhesions, leading to increased risk of developing the condition.
  • A study of 335 infertile women undergoing hysteroscopy revealed that over half showed signs of endometritis, with those having polyps having 5.2 times and those with adhesions having 4.6 times greater odds of the condition compared to those without these abnormalities.
  • The findings suggest that treating or removing these intrauterine issues could potentially lower the risk of chronic endometritis and enhance fertility, indicating a need for further investigation.
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