Publications by authors named "S Salazar"
Chitosan (CH)-based composite films have attracted increasing attention as promising green food packaging materials due to their biodegradability and ease of fabrication. Additionally, lignin (LN) has been widely used as additive for chitosan-based films to improve their physicochemical properties. In this study, a series of composite films made of chitosan nanoparticles (NCH) as a matrix and alkali lignin nanoparticles (LNPs) as functional filler were prepared.
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- Targeted electrical stimulation to specific thalamic regions could help patients with epilepsy who can't undergo surgery, but results vary significantly based on how well the stimulation aligns with the brain regions causing seizures.
- The study focused on three thalamic subnuclei and involved 32 patients to explore the connection between these nuclei and the areas of the brain where seizures start, using advanced imaging and electrophysiological techniques.
- Results showed that stimulating the properly matched thalamic nuclei effectively reduced seizure activities and frequency, with a 86.5% reduction for those with a specialized neurostimulation system, compared to only 39% effectiveness with standard methods.
Glucokinase (GK) catalyses the key regulatory step in glucose-stimulated insulin secretion. Correspondingly, hetero- and homozygous mutations in human cause maturity-onset diabetes of the young (GCK-MODY) and permanent neonatal diabetes (PNDM), respectively. To explore the possible utility of glucokinase activators (GKA) and of glucagon-like receptor-1 (GLP-1) agonists in these diseases, we have developed a novel hypomorphic allele in mice encoding an aberrantly spliced mRNA deleted for exons 2 and 3.
View Article and Find Full Text PDFIntroduction: Hemorrhage remains the leading cause of preventable death on the battlefield. The most effective means to increase survivability is early hemorrhage control and fluid resuscitation. Unfortunately, fluid resuscitation requires constant adjustments to ensure casualty is properly managed, which is often not feasible in the pre-hospital setting.
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- The success of equine assisted reproductive technologies (ART) is hindered by the limited storage time and motility of cooled stallion sperm during transport.
- Experiments tested whether controlling the temperature of shipping containers could extend the viability of cooled semen, revealing that sperm stored with specific temperature regulations showed better motility over time.
- Results indicated that maintaining sperm at a consistent 5 °C allowed for effective storage for over 7 days, significantly improving the logistics of ART.