Publications by authors named "S Sai Balakrishnan"
Modified Cajal's trichrome stain in oral squamous cell carcinoma.
J Oral Maxillofac Pathol
October 2024
Background: Modified Cajal's trichrome stain (MCTS) is a good differential stain that allows one to visibly distinguish between connective tissue and epithelial elements with different tonalities of colour.
Aim: Our study aims to evaluate and analyse the effectiveness of oral squamous cell carcinoma (OSCC) using MCTS.
Materials And Methods: A study was conducted retrospectively with 30 tissue blocks embedded in paraffin from cases of OSCC that have been confirmed by histopathology.
Correlation between Ki-67 labeling index and mitotic index in Head and neck squamous cell carcinoma.
Indian J Pathol Microbiol
October 2024
Background: Proliferative activity of any tissue or neoplasm can be determined by its growth rate by mitotic count or by using antibodies directed against specific antigens like Ki-67. The usefulness of Ki-67 in head and neck cancers has been debated for the past 20 years; however, no study has definitively resolved this controversy.
Aim: Assess the correlation between Ki-67 expression and mitotic index in head and neck squamous cell carcinoma.
Introduction: Insulin utilization pattern varies greatly in type 2 diabetes mellitus (T2DM) patients. Clinical inertia in treatment intensification hinders glycemic control in T2DM management. This study investigated insulin prescription trends and various predictors among insulin naive, user, and insulin inertia (II) patients in T2DM.
View Article and Find Full Text PDFArticle Synopsis
- Bisphenol A (BPA) is a common industrial chemical found in plastics, known for its toxic effects on aquatic life, including cytotoxicity and endocrine disruption.
- The study developed a new in vitro cell culture system from Daphnia magna embryos to conduct toxicity testing more ethically and efficiently, demonstrating that the cultures could be maintained for two months.
- Results showed that BPA exposure significantly increased antioxidant activity and gene expression related to stress responses while causing notable DNA damage, establishing the in vitro Daphnia model as a viable alternative to traditional methods in ecotoxicological research.
Flubendiamide, a phthalic acid diamide insecticide, has been implicated in potential teratogenic effects on non-target organisms, especially during embryonic development. This study examines the impact of flubendiamide on eye development in chick embryos, a well-established model for vertebrate development. Exposure to 0.
View Article and Find Full Text PDF