Publications by authors named "S Sadasivan"
Background: Wilson's disease (WD) results from pathogenic ATP7B gene variations, causing copper accumulation mainly in the liver, brain, and kidneys.
Objectives: In India, despite studies on ATP7B variants, WD often goes undiagnosed, with the prevalence, carrier rate, and mutation spectrum remaining unknown.
Methods: A multicenter study examined genetic variations in WD among individuals of Indian origin via whole exome sequencing.
The efficiency of H production water electrolysis is limited by the sluggish oxygen evolution reaction (OER). As such, significant emphasis has been placed upon improving the rate of OER through the anode catalyst. More recently, the Open Catalyst 2022 (OC22) framework has provided a large dataset of density functional theory (DFT) calculations for OER intermediates on the surfaces of oxides.
View Article and Find Full Text PDFBackground/aims: The aim of this study was to prospectively evaluate stereotactic body radiotherapy (SBRT) with robotic radiosurgery in hepatocellular carcinoma patients with macrovascular invasion (HCC-PVT).
Materials And Methods: Patients with inoperable HCC-PVT, good performance score (PS0-1) and preserved liver function [up to Child-Pugh (CP) B7] were accrued after ethical and scientific committee approval [Clinical trial registry-India (CTRI): 2022/01/050234] for treatment on robotic radiosurgery (M6) and planned with Multiplan (iDMS V2.0).
Article Synopsis
- Inflammation in prostate cancer involves changes in T and B cell levels, and the study investigates how these changes affect disease progression.
- The research analyzed 73 prostate cancer cases, measuring lymphocyte counts in pre- and postoperative samples from benign and malignant tissue using specific staining techniques.
- Findings indicate that higher levels of CD20+ lymphocytes in benign tissue adjacent to tumors are linked to a lower risk of cancer recurrence, highlighting the importance of immune response modulation in cancer prognosis.
Background: Hepatocellular carcinoma (HCC) is considered uncommon in India. The aim of this study was to document the demographic characteristics and clinical aspects of HCC in Kerala, India.
Methods: A survey of HCC in Kerala was performed.