Computationally grafting an IgE epitope onto a scaffold: Implications for a pan anti-allergy vaccine design.

Allergy is becoming an intensifying disease among the world population, particularly in the developed world. Once allergy develops, sufferers are permanently trapped in a hyper-immune response that makes them sensitive to innocuous substances. The immune pathway concerned with developing allergy is the Th immune pathway where the IgE antibody binds to its Fc RI receptor on Mast and Basophil cells.

Odd excitation of symmetric multimode interference structures.

In this work, we study the odd excitation of symmetric multimode interference (MMI) integrated optical structures. We develop a simple formula for the imaging length in the guide under odd excitation in the MMI structures using the symmetry of the structure. The obtained analytical results are verified by numerical calculations using the beam propagation method.

High-quality draft genome sequence of Flavobacterium suncheonense GH29-5(T) (DSM 17707(T)) isolated from greenhouse soil in South Korea, and emended description of Flavobacterium suncheonense GH29-5(T).

Flavobacterium suncheonense is a member of the family Flavobacteriaceae in the phylum Bacteroidetes. Strain GH29-5(T) (DSM 17707(T)) was isolated from greenhouse soil in Suncheon, South Korea. F.

Box-like filter response using multimode single-ring microresonators.

In this work we suggest a new technique to form a box-like filter response using a single microring resonator. The new design is based on exploiting the multimode propagation in the ring. The technique is implemented in the case of a two-mode ring resonator for different designs.

Development of an in vitro model system for studying the interaction of Equus caballus IgE with its high-affinity receptor FcεRI.

The interaction of IgE with its high-affinity Fc receptor (FcεRI) followed by an antigenic challenge is the principal pathway in IgE mediated allergic reactions. As a consequence of the high affinity binding between IgE and FcεRI, along with the continuous production of IgE by B cells, allergies usually persist throughout life, with currently no permanent cure available. Horses, especially race horses, which are commonly inbred, are a species of mammals that are very prone to the development of hypersensitivity responses, which can seriously affect their performance.