Publications by authors named "S Saarinen"
Developing bioinspired materials to convert sunlight into electricity efficiently is paramount for sustainable energy production. Fluorescent proteins are promising candidates as photoactive materials due to their high fluorescence quantum yield and absorption extinction coefficients in aqueous media. However, developing artificial bioinspired photosynthetic systems requires a detailed understanding of molecular interactions and energy transfer mechanisms in the required operating conditions.
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- The study investigates the phenomenon of non-return to work (non-RTW) among patients with Ischemic Heart Disease (IHD) over a year following their hospital discharge.
- It uses data from a national study that included 3,873 IHD patients who reported their mental and physical health through various assessment scales.
- Results show that about 38% of patients did not return to work after 12 months, with STEMI patients at the highest risk, indicating the importance of monitoring and supporting these individuals post-discharge to enhance their chances of returning to work.
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- Papillary thyroid cancer (PTC) is the most common type of thyroid cancer and can be inherited in families, prompting a study to find new genes and mechanisms linked to PTC susceptibility.
- Researchers focused on one family with PTC, using whole-genome sequencing, and also analyzed sporadic cases and familial adenomatous polyposis patients to search for genetic variants.
- They discovered specific gene variants in affected family members and found that the loss of the PDPR gene impacts glucose metabolism in thyroid cells, suggesting that PDPR might contribute to the risk of developing PTC.
Viral capsids can adopt various geometries, most iconically characterized by icosahedral or helical symmetries. Importantly, precise control over the size and shape of virus capsids would have advantages in the development of new vaccines and delivery systems. However, current tools to direct the assembly process in a programmable manner are exceedingly elusive.
View Article and Find Full Text PDFPurpose: In recent years, several new targeted therapies have emerged for advanced breast cancer (aBC). However, real-life data specific to aBC and different breast cancer subtypes are scarce. This retrospective cohort study was designed to describe the distribution of aBC subtypes, incidence, treatment patterns, survival, and PIK3CA hotspot mutation frequency.
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