Publications by authors named "S Saadat"
Introduction: Essential trace elements and micronutrients are critical in eliciting an effective immune response to combat sepsis, with selenium being particularly noteworthy. The objective of this investigation is to analyze and the levels of serum selenium in neonates within sepsis and control groups.
Methodology: In 2023, a case-control study was carried out involving 66 hospitalized infants - 33 diagnosed with sepsis forming the case group and 33 free from sepsis constituting the control group - along with their mothers, at Children's and Shariati Hospitals in Bandar Abbas.
Background: Zinc and copper are trace elements that have important roles in the function of the immune system. We aimed to compare serum zinc and copper levels in neonates with and without neonatal sepsis.
Methods: This case-control study examined 54 newborns with sepsis and 54 matched healthy controls admitted to the neonatal intensive care unit of Children's Hospital, Bandar Abbas, Iran.
Article Synopsis
- A significant number of consumers (48%) use generative AI for health inquiries, yet there is limited research on the quality of AI chatbot responses concerning emergency care advice.
- This study evaluated responses from four popular AI chatbots (ChatGPT, Google Bard, Bing AI, and Claude AI) using 10 emergency care questions, grading them across eight performance domains.
- Results showed that chatbots excelled in clarity and understandability (85%), had moderate accuracy and completeness (50%), but struggled with source relevance and reliability (10%), and potentially presented dangerous information in 5% to 35% of their responses.
Anti-HIV envelope broadly neutralizing antibodies (bnAbs) are alternatives to conventional antiretrovirals with the potential to prevent and treat infection, reduce latent reservoirs, and/or mediate a functional cure. Clinical trials with "first generation" bnAbs used alone or in combination show promising antiviral effects but also highlight that additional engineering of "enhanced" antibodies will be required for optimal clinical utility, while preserving or enhancing cGMP manufacturing capability. Here we report the engineering of an anti-CD4 binding-site (CD4bs) bnAb, N49P9.
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- - Vaccination has played a key role in reducing COVID-19 deaths and hospitalizations, but it can sometimes lead to autoimmune responses.
- - A case is reported of a 12-year-old girl developing systemic lupus erythematosus three weeks after her first Sinopharm BIBP COVID-19 vaccine dose.
- - Despite the reported potential link between vaccines and autoimmune disorders, vaccination is still recommended as the benefits of preventing COVID-19 far outweigh the risks.