Publications by authors named "S S de la Pena"
Background and aim The study aimed to investigate the effect of adding perineural adjuvants, clonidine and dexamethasone, to local anesthetic in Superficial Parasternal Intercostal Plane (SPIP) blocks. It was designed as a prospective, randomized, triple-blinded, feasibility trial, conducted at a single-center university hospital. The participants included adult patients who were undergoing cardiac surgery via median sternotomy.
View Article and Find Full Text PDFImportance: Among older adults with ischemic heart disease, participation in traditional ambulatory cardiac rehabilitation (CR) remains low. While mobile health CR (mHealth-CR) provides a novel opportunity to deliver care, age-specific impairments to technology use may limit uptake, and efficacy data are currently lacking.
Objective: To test whether mHealth-CR improves functional capacity in older adults.
High-harmonic generation (HHG) is a nonlinear process in which a material sample is irradiated by intense laser pulses, causing the emission of high harmonics of incident light. HHG has historically been explained by theories employing a classical electromagnetic field, successfully capturing its spectral and temporal characteristics. However, recent research indicates that quantum-optical effects naturally exist or can be artificially induced in HHG, such as entanglement between emitted harmonics.
View Article and Find Full Text PDFArticle Synopsis
- The study focuses on identifying genetic mutations in malaria parasites that confer drug resistance, essential for improving surveillance and target discovery in malaria treatment.
- Researchers analyzed the genomes of 724 clones resistant to 118 different antimalarial compounds, uncovering 1,448 variants in 128 frequently mutated genes related to multidrug resistance.
- The findings suggest that in vitro selected mutations are more diverse and significant than naturally occurring ones, providing insights into how these mutations can inform predictions of drug resistance in similar pathogens.
Article Synopsis
- Hypertension is a significant risk factor for ischemic heart disease in older adults, and effective home blood pressure monitoring (HBPM) is crucial for management, especially within mobile health cardiac rehabilitation (mHealth-CR).
- A study analyzed the engagement patterns of 111 older adults participating in mHealth-CR, revealing three distinct patterns of HBPM adherence: high engagement, gradual decline, and sustained baseline engagement.
- Results indicated that overall HBPM adherence was low, declining in two engagement groups, and only depression significantly influenced weekly monitoring adherence, suggesting a need to improve motivation and support for older adults in managing their blood pressure.