Data-driven cluster analysis identifies distinct types of metabolic dysfunction-associated steatotic liver disease.

Metabolic dysfunction-associated steatotic liver disease (MASLD) exhibits considerable variability in clinical outcomes. Identifying specific phenotypic profiles within MASLD is essential for developing targeted therapeutic strategies. Here we investigated the heterogeneity of MASLD using partitioning around medoids clustering based on six simple clinical variables in a cohort of 1,389 individuals living with obesity.

How to Manage a Large Undifferentiated Lung Cancer Mass: A Case Report.

Non-small cell lung cancer is the most common type of lung cancer globally. An important subtype to discuss is undifferentiated carcinomas, which are variants of large cell carcinoma, and these can typically present with evidence of neuroendocrine differentiation. The patient presented with a large mass in the right upper lobe extending into the middle lobe.

A case of asymptomatic giant renal angiomyolipoma with extrusion of fat content with literature review.

Angiomyolipoma is a benign mesenchymal tumour of kidney that consists of adipose tissue, muscle cells and blood vessels. Renal angiomyolipomas represent almost one percent of all renal tumours. We reported a case of a 50-year-old woman complaining of mild abdominal discomfort with no other symptoms and no remarkable medical history.

Accuracy of Three Commercial Wearable Devices for Sleep Tracking in Healthy Adults.

Sleep tracking by consumers is becoming increasingly prevalent; yet, few studies have evaluated the accuracy of such devices. We sought to evaluate the accuracy of three devices (Oura Ring Gen3, Fitbit Sense 2, and Apple Watch Series 8) compared to the gold standard sleep assessment (polysomnography (PSG)). Thirty-five participants (aged 20-50 years) without a sleep disorder were enrolled in a single-night inpatient study, during which they wore the Oura Ring, Fitbit, and Apple Watch, and were monitored with PSG.