Publications by authors named "S S Witkin"

can inhibit the growth of multidrug-resistant organisms (MDROs) and modulate the gut microbiome. However, data on hematopoietic stem cell transplantation (HSCT) are scarce. In an observational study, we assessed the impact of on the modulation of the gut microbiome in HSCT patients colonized by MDROs.

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The lower female reproductive tract (FRT) hosts a complex microbial environment, including eukaryotic and prokaryotic viruses (the virome), whose roles in health and disease are not fully understood. This review consolidates findings on FRT virome composition, revealing the presence of various viral families and noting significant gaps in knowledge. Understanding interactions between the virome, microbiome, and immune system will provide novel insights for preventing and managing lower genital tract disorders.

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Unlabelled: Cervical cancer, whose well-recognized etiological agent is the Human Papillomavirus (HPV), is responsible for approximately 300,000 deaths worldwide, 80% of cases occurring in developing countries. In Brazil, 17,010 cases were expected, with 2,550 cases in São Paulo State, in 2023. The Papanicolaou test is the diagnostic method for the detection of precancerous lesions of the cervix, and HPV vaccination is now available for prevention.

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Article Synopsis
  • A CRESS-DNA virus, primarily found in fecal samples from vertebrates, was examined in human vaginal samples for its presence.
  • Viral metagenomics was conducted on samples from 28 healthy women in NYC, with some providing duplicates over a 12-21 day span.
  • The study found that one individual had continuous detection of the CRESS-DNA virus over a twelve-day period, indicating it can persist in the human vagina.
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Article Synopsis
  • * Out of 29 women studied, 18 tested positive for HPV, showing a significant increase from initial visits to after hormone stimulation.
  • * Analysis identified various HPV types, notably under two genera, with some sequences potentially representing new types.
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