Publications by authors named "S S Wing"
Background: Chronic kidney disease (CKD) is a common complication after acute kidney injury (AKI). We aimed to evaluate whether RRT initiation strategy had an effect on CKD progression. Secondarily, we aimed to identify factors that influenced the development or progression of CKD following severe AKI.
View Article and Find Full Text PDF-Synuclein ubiquitination - functions in proteostasis and development of Lewy bodies.
Front Mol Neurosci
November 2024
Article Synopsis
- * Ubiquitination plays a crucial role in regulating -synuclein's behavior in cells, affecting how it's degraded, how it aggregates, and its potential neurotoxic effects.
- * The review highlights the mechanisms behind -synuclein ubiquitination, emphasizing the roles of E3 ligases and deubiquitinases, and suggests that understanding these processes could lead to new treatments for synucleinopathies.
A long-term record of global mean surface temperature (GMST) provides critical insight into the dynamical limits of Earth's climate and the complex feedbacks between temperature and the broader Earth system. Here, we present PhanDA, a reconstruction of GMST over the past 485 million years, generated by statistically integrating proxy data with climate model simulations. PhanDA exhibits a large range of GMST, spanning 11° to 36°C.
View Article and Find Full Text PDFArticle Synopsis
- Privilege and marginalization based on racial background contribute to disparities in care and recovery for Black athletes facing sport-related concussions (SRC).
- A qualitative content analysis was performed to explore existing literature on racial differences in SRC outcomes, revealing biased beliefs and limited access to concussion resources for Black athletes.
- The study developed a novel ecological-systems framework to illustrate how broader socio-cultural and historical factors influence individual clinical decisions and care for Black athletes with SRC.