Next-generation pharmaceuticals: the rise of sildenafil citrate ODF for the treatment of men with erectile dysfunction.

Orodispersible film (ODF) is one of the novel formulations that disintegrate rapidly in the mouth without the requisite for water compared to other conventional oral solid dosage formulations. This delivery system serves as a convenient mode of administration, especially in patients who have dysphagia and fluid restriction, being beneficial to pediatric, geriatric, and bedridden patients. A novel sildenafil ODF containing sildenafil citrate is formulated to be used in patients with erectile dysfunction (ED).

Bifunctional hierarchical WO nanorods@Br-doped g-CN Z-scheme heterojunctions for efficient tetracycline photodegradation: Optimization of key parameters, toxicological assessment, and electrocatalytic hydrogen evolution reaction.

In this study, graphitic carbon nitride (CN) and tungsten trioxide (WO) were successfully incorporated into bromine (Br)-doped graphitic carbon nitride (BCN) using an in-situ hydrothermal method. The photocatalytic efficiency of the resulting WO/Br-doped CN (WBCN) composites for the removal of tetracycline (TC) antibiotics under sunlight irradiation was evaluated. The mass ratio of WO to Br-doped CN (BCN) significantly influenced TC adsorption and photocatalytic degradation, with an optimal ratio of 9:1.

Suitability, acceptability, feasibility of modern menstrual methods: a qualitative study in Coimbatore district, Tamil Nadu, India.

Objective: To examine women's perceptions of modern menstrual hygiene methods (MMHM), such as tampons and menstrual cups, focusing on socio-demographic variations and special groups in the Coimbatore district of Tamil Nadu.

Methods: A qualitative study among women of reproductive age (15-49 years) group was conducted using Focus Group Discussions (FGDs) among twelve women subgroups independently in 2023.

Results: The present study involved 23 focus group discussions (FGDs) across various groups of women, including those in formal and informal sectors, urban and rural areas, school and college students, healthcare workers, women in sports, tribal women, transgender women, and female sex workers (FSW), with a total of 188 participants.

MnCoO Nanostructure Anchored on Functionalized Carbon Black for the Enhanced Bifunctional Electrocatalytic Performance of OER and HER.

The electrocatalytic oxygen and hydrogen evolution reactions (OER and HER) are key processes used in energy storage and conversion. We have developed a highly efficient MnCoO nanostructure anchored with functionalized carbon black (MnCoO/f-CB), which has been characterized by XRD, FT-IR, Raman spectra, FE-SEM, and HR-TEM analyses as robust bifunctional electrocatalysts for both HER and OER. At a characteristic 10 mA cm current density, the MnCoO/f-CB composite ECs exhibit low overpotentials of 330 mV for OER and 360 mV for HER, respectively.

Outcomes of Endovascular Treatment for Salvaging Failed Hemodialysis Arteriovenous Fistula - Role of Balloon Angioplasty as Initial Therapy.

Background: This study aims to evaluate the technical and clinical outcomes of endovascular treatment for failed native hemodialysis fistulas, mainly the role of balloon angioplasty in salvaging thrombosed and stenosed arteriovenous fistulas.

Materials And Methods: This retrospective study was done on 23 patients who had presented with non-functioning dialysis fistulas. The mean age of the patients was 58.