[Steadfastly increased level of the ciliary neurotrophic factor in the blood serum within the positive therapeutic dynamics of depression as possible prognostic marker of depressive relapse].

Objective: To study a role of the ciliary neurotrophic factor (CNTF) in the pathogenesis of depression and its prognostic significance in dynamics of the antidepressant therapy.

Material And Methods: CNTF level was investigated in the blood serum of patients with melancholic depression (=32) before the start of therapy and after 30 days, when improvement was achieved by at least 75% of baseline scores on the Hamilton Depression Rating Scale.

Results: Steadfastly increased level of CNTF in the blood serum of patients with melancholic depression compared with the control, remaining practically unchanged with an obvious improvement in the condition - 732.

[Some aspects of metabolic dysregulation in patients with ischemic stroke].

To study the mechanisms of formation of an endogenous intoxication syndrome in patients after ischemic stroke, the activity of platelet monoaminooxidase (MAO) and serum aminooxidase, concentration of middle-size molecules and parameters of functional albumin activity have been determined in 27 patients with illness duration 4-5 months and 16 healthy age- and sex-matched controls. The significant dysregulation of biogenic amine metabolism and total homeostasis was observed in patients compared to controls. There were a significant increase of MAO and concentration of middle-size molecules and a decrease of aminooxidase and functional albumin activity (p < 0.

[Estimation of the sanitary and microbiological indices of stored and bacteriophaged milk].

The paper gives data on the microbiological study of raw milk delivered by various suppliers to a reprocessor. More than 57.3% of the farms are shown to deliver abnormal milk of poor and very poor sanitary quality.

[Prediction of individual radio-resistance in animals by the parameters of initial endocrine functioning of the organism].

Predictability of individual radioresistance by initial parameters of endocrine functions, i.e. peripheral blood levels of adrenal hormones (corticosterone) and thyroid hormones (triiodthyronin and thyroxin) was tested.

Some neurotropic effects of low-intensity electromagnetic waves in rats with different typological characteristics of higher nervous activity.

The effects of low-intensity electromagnetic waves (4200 MHz, modulated with quasichaotic signals at 20-20,000 Hz, energy density 15 microW/cm2; specific energy absorption not greater than 15 mJ/kg) on the neurochemical systems of the brain and on behavioral reactions were studied in experimental animals with different typological characteristics of higher nervous activity. These studies showed that electromagnetic waves produced marked changes in the state and activity of the monoaminergic mediator systems which were in general terms concordant with changes at the integrative level (mostly selective inhibitory effects). The nature of these processes depended to a significant extent on the typological characteristics of the animals.