Publications by authors named "S S Sheen"
Article Synopsis
- Clinical interest in peripheral nerve stimulation (PNS) has grown due to its potential benefits for chronic pain management over traditional medications, but variability in its use persists due to the lack of clear guidelines and standardized systems.
- A survey of 94 pain physicians revealed that PNS is most commonly used for neuropathic pain conditions, such as peripheral neuralgia, while its application for nociceptive pain like chronic low back pain and osteoarthritis shows mixed results.
- The study highlights the common practice of conducting nerve blocks prior to PNS for anatomical verification, with practitioners seeking a minimum 50% to 75% pain relief as a requirement to proceed with treatment.
Lead migration is a common complication of spinal cord stimulation, although anterior migration is rare. While early studies suggested that anterior stimulation may produce analgesic effects, it is thought to be poorly tolerated due to abnormal paresthesia and muscle contractions due to its proximity to the corticospinal tract. This case report presents a unique case of sustained pain relief despite anterior lead migration, which suggests that anterior column stimulation may hold clinical significance for pain management.
View Article and Find Full Text PDFThere is a lack of evidence-based standards for matching spinal cord stimulation (SCS) paradigm to individual patients. We aim to determine the feasibility and safety of a new alternative trial strategy, a sequential multidevice trial. A retrospective analysis was performed on 116 patients who underwent SCS trials, single device or sequential multidevice (tonic and high-frequency), for chronic low back pain to assess feasibility and compare trial-to-implantation rate and explantation rate.
View Article and Find Full Text PDFEpidemiology and Functional Outcome of Acute Stroke Patients in Korea using Nationwide data.
J Korean Neurosurg Soc
September 2024
Article Synopsis
- Korea's healthcare system emphasizes early and proactive treatment for stroke to enhance patient outcomes, as indicated by a study on stroke epidemiology and outcomes.
- Data from over 86,000 acute stroke patients were analyzed, revealing that ischemic stroke was the most prevalent type, followed by intracerebral and subarachnoid hemorrhages.
- The study showed that 49.6% of patients arrived at hospitals within 4.5 hours of symptom onset, leading to good functional outcomes in 58.3% of patients, with variations in prognosis based on the type of stroke.
Article Synopsis
- Genomic alterations in tumors significantly influence cancer progression and treatment response, with whole-genome sequencing (WGS) emerging as a viable alternative to traditional targeted panel sequencing (TPS) due to advancements in cost and technology.
- A study involving 120 cancer patients evaluated the clinical utility of WGS and found that 79% received genomic reports quickly, with 72% of these reports offering clinically relevant information.
- The insights gained from WGS helped in selecting tailored treatments and clinical trials based on identifying specific mutations, potentially enhancing precision oncology and suggesting routine integration of WGS in cancer management.