Publications by authors named "S S Sathaye"

Article Synopsis
  • - Dry eye disease (DED) is a complex eye condition, and this review summarizes current and future treatment options for it by looking at research from PubMed, FDA, and other databases.
  • - Current FDA-approved treatments for DED include several cyclosporine formulations, lifitegrast (XIIDRA), and various medical devices designed to improve tear production and treat meibomian gland dysfunction.
  • - Numerous clinical trials are ongoing to evaluate new treatments for DED, including various novel drops and solutions, aiming to enhance symptomatic relief as well as overall management of the disease.
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Correction for 'Molybdenum-maltolate as a molybdopterin mimic for bioinspired oxidation reaction' by Swapnil S. Pawar , , 2024, , 5770-5774, https://doi.org/10.

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A novel -dioxomolybdenum(VI)-maltolate [MoO(Mal)] (1) is prepared as a stable molybdopterin model for the biomimetic catalysis of the oxidation of hypoxanthine in acetonitrile-water at room temperature. Compound 1 efficiently catalyzes the oxidation reaction of toluene, diphenylmethane, and styrene. Cyto- and oral-toxicity studies suggest its tremendous potential for application as a molybdenum supplement.

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This study was aimed at investigating the neuroprotective potential of a co-extract obtained by supercritical fluid extraction (SFE) of turmeric powder and dried coconut shreds against aluminium chloride (AlCl)-induced Alzheimer's disease (AD) in male Wistar rats. Fifty animals were allocated to five groups, which received saline (vehicle control, group 1), a combination of saline and aluminium chloride (AlCl) (disease control, group 2), coconut oil (COO) (SFE extracted, treatment group 3), turmeric oleoresin (Cur) (SFE extracted, treatment group 4) and SFE co-extract of turmeric powder and coconut shreds (CurCOO) (treatment group 5). Animals were subjected to behavioural evaluation.

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Phloretin (PHL), a flavonoid of the dihydrogen chalcone class, is reported to have low oral bioavailability due to its poor solubility and absorption. A common approach to enhance the solubility of such flavonoids is solubilization in a polymeric or lipidic matrix which would help in enhance dissolution rate and solubility. Accordingly, in the current study PHL was dissolved in Gelucire® 44/14 by melt-fusion technique and the viscous semisolid melt was adsorbed on a solid carrier to obtain free flowing granules.

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