Publications by authors named "S S Safal"

Background: Different treatment approaches exist for non-ST elevation acute coronary syndrome (ACS) patients. This study assessed the systemic immune inflammatory response index (SIIRI) for its prognostic value and incremental clinical utility in determining optimal timing for percutaneous coronary intervention (PCI) in non-ST elevation myocardial infarction (NSTEMI) patients, particularly when troponin levels are initially negative.

Methods: This study included 1270 ACS patients: 437 STEMI, 422 NSTEMI, and 411 unstable angina.

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  • The study focused on non-ischemic symptomatic reversible bradyarrhythmia, a condition that can be often misunderstood in clinical settings, aiming to determine how often it recurs and the predictors for needing permanent cardiac pacing.
  • It included 124 adults monitored for up to 24 months after conservative treatment, finding that 21.8% required permanent pacing due to recurrence, with common causes being certain medications and high potassium levels.
  • Key predictors for needing pacing included advanced atrioventricular block and bifascicular block observed during the patient's initial hospitalization, highlighting the need for closer monitoring and potential intervention.
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  • Culotte stenting is a treatment method for bifurcation lesions of the left main coronary artery that has proven effective but can lead to side branch restenosis due to gaps at the ostium.
  • A study found that performing sequential kissing balloon dilation before main vessel stenting can help prevent these gaps, which is important for successful outcomes.
  • In a report of 45 patients treated with double kissing mini-culotte stenting, there were no major adverse events, and the procedure showed low rates of complications and side branch restenosis at the one-year follow-up.
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Introduction: Contrast-induced nephropathy (CIN) is a common complication after percutaneous coronary intervention (PCI). There is conflicting evidence regarding efficacy of nicorandil in CIN prevention. With respect to ranolazine, there is physiological possibility as well as data in animal study regarding its protective effect against CIN; there is, however, no human data till date.

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