Publications by authors named "S S Raychoudhury"

Epididymis plays a vital role in promoting sperm maturation and maintaining sperm viability. It has been shown the presence of nonviable sperm in cauda epididymis. We previously identified a secretory protein (260/280KDa oligomers) of hamster cauda epididymal principal cells that binds to nonviable sperm.

View Article and Find Full Text PDF

The luminal environment of the mammalian epididymidis performs a dual function; sperm maturation and maintaining sperm viability. We previously identified a secretory protein (260/280KDa oligomers) of hamster cauda epididymal principal cells that binds to nonviable sperm. The 260/280KDa oligomers are composed of 64kDa FGL2 (fibrinogen-like protein-2) and 33kDa FGL1) (fibrinogen-like protein-1).

View Article and Find Full Text PDF

This paper aims to further our previous study to investigate the effect of speed on the human metatarsophalangeal (MP) joint kinematics during running on level ground. The 3D motion of the foot segments was captured by a twelve-camera motion analysis system, and the ground reaction forces and moments were recorded by using a six-force plate array. The relative movement between the tarsometatarsi (hindfoot) and phalanges (forefoot) segments were recorded to obtain the 3D orientation and position of the functional axis (FA) of the MP joint.

View Article and Find Full Text PDF
Article Synopsis
  • Infants and children are at risk for early exposure to microcystin, a toxin from harmful algal blooms, which may lead to health issues later in life.
  • A study tested how early exposure to microcystin combined with a high-fat diet impacts the development of nonalcoholic fatty liver disease (NAFLD) in adulthood, revealing inflammation symptoms and increased inflammatory markers in exposed groups.
  • Mice lacking the NLRP3 inflammasome (NLRP3 KO) showed less inflammation and metabolic issues, suggesting that childhood exposure to microcystin could negatively affect liver health through NLRP3 activation.
View Article and Find Full Text PDF

Polycyclic Aromatic Hydrocarbons (PAHs) are environmental pollutants. The present study compares the toxic effects of BaP alone and a mixture of PAHs on human breast cancer cells. We hypothesize that PAH mixture is more toxic than BaP alone, and an increased NOX2 activation is related to PAH-induced oxidative stress.

View Article and Find Full Text PDF