Publications by authors named "S S Perry"

X-ray crystallography is one of the leading tools to analyze the 3-D structure, and therefore, function of proteins and other biological macromolecules. Traditional methods of mounting individual crystals for X-ray diffraction analysis can be tedious and result in damage to fragile protein crystals. Furthermore, the advent of multi-crystal and serial crystallography methods explicitly require the mounting of larger numbers of crystals.

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This Letter presents complex coacervation between the biopolymer diethylaminoethyl dextran hydrochloride (DEAE-Dex) and carbon dots. The formation of these coacervates was dependent on both DEAE-Dex concentration and solution ionic strength. Fluorescence spectroscopy revealed that the blue fluorescence of the carbon dots was unaffected by coacervation.

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Background: Thiotepa-based autologous stem cell transplantation (ASCT) improves survival in primary central nervous system lymphoma (PCNSL), but > 30% of patients are unable to undergo ASCT following commonly used intensive induction regimens.

Methods: This retrospective population-based study included consecutive patients ≥ 18 years old with PCNSL who were intended for ASCT in Alberta, Canada between 2011 and 2022. A reduced-intensity induction protocol was further abbreviated in 2018 to decrease toxicity and expediate ASCT by incorporating rituximab, procarbazine, and only 2 doses of high-dose methotrexate and 1 cycle of high-dose cytarabine before consolidation with thiotepa-busulfan conditioning.

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Article Synopsis
  • Word identification accuracy is influenced by factors like word frequency, listening environments, and listener age, with younger and older adults showing different levels of performance, particularly in noisy settings.
  • This study investigates how both age groups perceive speech-in-noise, specifically focusing on medically related terms that vary in familiarity and frequency within simulated hospital noise, highlighting the challenges older adults face.
  • Findings revealed that older adults struggle more with low-familiarity medical words in hospital noise compared to younger adults, emphasizing the need for better communication strategies in healthcare settings.
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  • * Postmortem examinations showed that the manatee suffered from various health issues, including aortic stenosis, left ventricular hypertrophy, and a plastic bag lodged in its esophagus, alongside cold stress symptoms.
  • * Blood tests indicated systemic inflammation and potential coagulation problems, while heart-related findings included severe cardiac abnormalities; however, the exact cause of these cardiovascular issues remains undetermined.
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